… first clinical implantations were reported in 1990 albeit simultaneously with results of Rashkind’s
double umbrella … and use them accordingly for each specific subgroup of defects. Long-…

… occluders currently used in clinical applications and under development… Early in 1974,
King and Mills reported for the first time the transcatheter closure of ASD using a double-umbrella …

… first review examining the outcomes of single versus multiple device ASD closure in adults
with ostium secundum defects… the use of additional devices for distinctly separate defects. For …

… (ASD) occluder finally coming into clinical use, which is made of … Finally in this manuscript,
the first clinical transcutaneous … occluder is of a “double-umbrella” framework with meshes …

… have been used in clinical applications. Considering that the … Not only can this kind of device
close the defect and provide … of a self-expandable “double-umbrella” PLLA framework and …

… currently used in clinical applications and under development… The INTRASEPT was the
first double-umbrella PFO device … A multicenter study reported the first clinical experience with …

… clinical use for varied reasons will be reviewed first. The devices not yet approved by the FDA
will be mentioned and then, the devices currently in use and … The first clinical study with the …

… the first transcatheter ASD closure using a double-umbrella device in … BioSTAR Evaluation
Study was the first clinical trial … available for defect closure: type small (to close defects 4 to …

… septal defect (VSD), atrial septal defect, and left atrial … framework shaping into a double-umbrella
and recover support … and precluded its approval for clinical use in North America. We …

… double umbrella version of the device, but, pending clinical trials, the device did not reach
clinical use… buttoned device was found feasible and effective in closing atrial septal defects. …